Mibolerone is a steroid hormone designed for oral use. It is a derivative of nandrolone: structurally it is its 7, 17 demethylated modification; it is characteristically characterized as a substance of pronounced androgenic (androgenic index ≈ 250% of endogenous testosterone) and corresponding anabolic (anabolic index ≈ 590% of endogenous testosterone) activity with a fast action (half-life ≈ 2-4 hours).
Mibolerone (Cheque Drops, after the name of the most common brand name) was obtained by chemical modification of nandrolone in two positions: the first is the 17a-methyl group, which prolongs the period of action and adds to the substance resistance to destruction by the liver when taken orally; the second is the 7a-methyl group, which increases the effectiveness of the substance by inhibiting 5-alpha reductase, increasing resistance to SHBG binding and improving biological activity.
Mibolerone steroid effects
The steroid mibolerone, like most sports pharmacology that is relevant today, was originally produced not at all for doping, but for medicinal use. It was successfully synthesized in the 60s of the 20th centuries after which it became widely used in veterinary practice: for example, it was used to interrupt the ovulation cycle in dogs during estrus. As a pharmacological drug, it is still officially available in the United States, but is released only under a veterinary license.
As sports doping, mibolerone preparations are used primarily before training and competition, respectively, to increase intensity and improve performance. It provokes a surge of adrenaline, contributes to the maximum increase in aggression, endurance, and strength indicators, due to which it is in demand in strength and athletics sports. For safety, it is used only in short courses and at a low dosage and is recommended for athletes experienced in sports pharmacology. For women and beginners in sports, there are analogues that are more advantageous in terms of effectiveness / safety, such as oral turinabol, methandienone, methenolone enanthate or boldenone undecylenate.
Customer reviews describe mibolerone for sale mostly positively but warn that it is one of the strongest androgens available on the sports pharmacology market (if not the strongest!).
Due to the high androgenicity, the use of mibolerone preparations for sports purposes is justified only for men. For women who decide to use it, the threat is androgen-conditioned virilization, which is expressed by symptoms such as acne, hair growth, excitability, greasy skin, even menstrual irregularities.
The average recommended dosage of mibolerone for men is 250-500 mcg (0.25-0.5 mg) per day. There are known cases of using up to 1000 mcg (1 mg) of a steroid per day, but for the majority of those using such amounts are unacceptable, since they provoke the development of somatic diseases. The working dose is selected exclusively individually, otherwise it may be insufficient or, conversely, excessive.
The course of mibolerone use is on average short ≈ 2-4 whole weeks: it is advisable to use the steroid directly before training or competitions to develop results, and long-term use threatens to shift activity towards androgenic and estrogenic side effects.
Since athletes are taking mibolerone off-label, they are advised to be examined in advance to rule out contraindications and to consult a specialist for instructions. Only in this way can you guarantee yourself the absence of short-term or long-term consequences of the courses.
Side Effects of Mibolerone
Side effects of mibolerone include androgenic (from acne to head baldness), estrogenic (from water retention to estrogenic gynecomastia) and progestogenic (from impaired libido to progestin gynecomastia) complications, as well as the consequences of hepatotoxicity (decreased natural liver function). Due to the risks associated with a heavy steroid cycle, concomitant use of an antiestrogenic, as an aromatase inhibitor anastrozole (Anastrodin), and an antiprogestogen, as a blocker of prolactin secretion, cabergoline (Dostinex), may be required, which prevent the corresponding side effects.
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