A New Way to Build Muscle While Losing Fat

man back building muscle in dark

First created by Glaxo Smith Kline and Ligand Pharmaceuticals in 1992, GW-501516 (Cardarine) is a SARMS that binds to the Peroxisome proliferator-activated receptor (PPARs). Cardarine, when binding to the PPAR receptor, recruits the coactivator PGC-1a (a transcriptional coactivator that is the central inducer of mitochondrial biogenesis in cells) enzyme. This stimulates an increase in the […]

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